School of Molecular Biosciences

SMB Faculty Research Interests

Biochemistry & Structural Biology
Margaret Black SMB Interests: Nucleotide metabolism.	John Browse IBC Interests: Lipids in membrane function and cellular signaling.
Bill Davis SMB Interests: DNA oxidative damage and repair.	Lisa Gloss SMB Interests: Protein folding and macromolecular assembly: histones, the nucleosome and halophilic enzymes.
Joseph Harding VCAPP Interests: Role of neuropeptides in brain-angiotensin system.	Chul Hee Kang Chemistry Interests: Calcium metabolism in cardiac myocyte and cardiac side effect of pharmaceutical compounds.
Mark Lange IBC Interests: Isoprenoid metabolism in plants.	Subra Muralidharan SMB Interests: Structures, functions, and applications of nanoscale biological systems.
Raymond Reeves SMB Interests: HMGA regulation of transcription.	Susan Wang SMB Interests: Radical mechanisms in enzyme catalysis.
Luying Xun SMB Interests: Microbial degradation of xenobiotics.

Cell Biology and Cellular Signaling
John Alderete SMB Interests: The study of parasite and host cell-tissue interactions focused on proteins that contribute to infection and disease pathogenesis.	John Browse IBC Interests: Lipids in membrane function and cellular signaling.
Cynthia Cooper SMB Interests: Zebrafish developmental mechanisms.	Joseph Harding VCAPP Interests: Role of neuropeptides in brain-angiotensin system.
Chengtao Her SMB Interests: Mammalian DNA mismatch repair pathways.	Mary Hunzicker-Dunn SMB Interests: Signaling pathways leading to activation of target genes in ovarian granulosa cells directed by follicle-stimulating hormone or luteinizing hormone.
Kwan Hee Kim SMB Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.	Nancy Magnuson SMB Interests: Role of Pim-1 cellular proliferation and differentiation.
David Moffett SBS Interests: Cell biology of epithelial transport, particularly mechanisms for generating extremely alkaline secretions	Eric Shelden SMB Interests: Shock proteins in zebrafish development, regeneration and aging.
Jennifer Watts SMB Interests: Genetics and genomics of lipid metabolism and fat storage in C. elegans.

Chromatin, DNA Repair and Cancer
Wenfeng An SMB Interests: Mechanisms of mammalian LINE-1 retrotransposition and applications in functional genomics.	Margaret Black SMB Interests: Suicide gene therapy of cancer.
Weihang Chai SMB Interests: Telomere structure, maintenance and function.	Bill Davis SMB Interests: DNA oxidative damage and repair.
Lisa Gloss SMB Interests: Protein folding and macromolecular assembly: histones, the nucleosome and halophilic enzymes.	Cynthia Haseltine SMB Interests: Mechanisms of homologous recombination and cellular responses to DNA damage in hyperthermophilic archaeal microbes.
Terry Hassold SMB Interests: Meitoic chromosome abnormalities.	Chengtao Her SMB Interests: Mammalian DNA mismatch repair pathways.
Chul Hee Kang SMB Interests: Calcium metabolism in cardiac myocyte and cardiac side effect of pharmaceutical compounds.	Nancy Magnuson SMB Interests: Role of Pim-1 cellular proliferation and differentiation.
Subra Muralidharan SMB Interests: Structures, functions, and applications of nanoscale biological systems.	Raymond Reeves SMB Interests: HMGA regulation of transcription.
Michael Smerdon SMB Interests: DNA excision repair in the context of chromatin structure.	Grant Trobridge Pharmaceutical Sciences Interests: Oncogene discovery using retroviruses.
John Wyrick SMB Interests: Histone modifications in global gene expression.	Ping Ye SMB Interests: Bioinformatic, computational, and experimental analyses of cellular responses to pathogens and stimuli.

Microbial Genetics, Physiology and Infectious Disease
Hector Aguilar-Carreno VMP Interests: Entry mechanisms of highly pathogenic zoonotic viruses into mammalian cells.	John Alderete SMB Interests: The study of parasite and host cell-tissue interactions focused on proteins that contribute to infection and disease pathogenesis.
Kelly Brayton Vet. Micro. Path. Interests: Infectious diseases, microbial genomics, mechanisms of persistence.	Doug Call VMP Interests: Evolution and persistence of antibiotic resistance; molecular epidemiology; comparative genomics, transcriptomics, and proteomics of pathogens; detection pathogens in complex matrices; and aquaculture health.
Matthias Hess SMB(TriCities) Interests: Enhancing our understanding of microbial systems and how microbial communities and single microbes shape the world we live in.	Michael Kahn SMB and IBC Interests: Genetics, genomics and metabolism of plant-microbe interactions.
Michael Konkel SMB Interests: Campylobacter jejuni pathogenic determinants.	Audrey Lau Vet. Micro Path. Interests: Host-pathogen interactions in Apicomplexan parasites using microbial genomics and proteomic approaches. I am also interested in vaccine and drug discovery.
Anthony Nicola VMP Interests: Cell biology of virus-host interactions, herpesviruses, viral entry, membrane fusion, envelope glycoproteins, viral pathogenesis.	Linda Thomashow USDA Research Geneticist Interests: Pseudomonas genes involved in interactions with wheat.
Grant Trobridge Pharmaceutical Sciences Interests: Stem cell gene therapy for HIV infection.	Susan Wang SMB Interests: Radical mechanisms in enzyme catalysis.
Luying Xun SMB Interests: Microbial degradation of xenobiotics.	Ping Ye SMB Interests: Bioinformatic, computational, and experimental analyses of cellular responses to pathogens and stimuli.

Molecular Genetics, Gene Regulation and Chromosome Biology
Wenfeng An SMB Interests: Mechanisms of mammalian LINE-1 retrotransposition and applications in functional genomics.	Weihang Chai SMB Interests: Telomere structure, maintenance and function.
Cynthia Cooper SMB Interests: Zebrafish developmental mechanisms.	Michael Griswold SMB Interests: Role of Sertoli cells in mammalian spermatogenesis.
Cynthia Haseltine Assistant Professor, SMB Interests: Mechanisms of homologous recombination and cellular responses to DNA damage in hyperthermophilic archaeal microbes.	Terry Hassold SMB Interests: Meitoic chromosome abnormalities.
Pat Hunt SMB Interests: Mammalian germ cell development and meiotic cell cycle control.	Kwan Hee Kim SMB Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.
Michael Konkel SMB Interests: Campylobacter jejuni pathogenic determinants.	John Nilson SMB Interests: Molecular mechanisms underlying temporal, spatial, and hormonal regulation of gene expression in pituitary gonadotropes. Developing mouse models that allow mechanistic interrogation of the hypothalamic-pituitary-gonadal (HGP) axis within a physiological setting.
B. Dan Rodgers Animal Sciences Interests: Molecular endocrinology and genomics of muscle development.	Eric Shelden SMB Interests: Heat shock proteins in drug resistance.
Michael Smerdon SMB Interests: DNA excision repair in the context of chromatin structure.	Gary Thorgaard SBS Interests: Genetic analysis of complex traits in trout and salmon.
Jennifer Watts SMB Interests: Genetics and genomics of lipid metabolism and fat storage in C. elegans.	John Wyrick SMB Interests: Histone modifications in global gene expression.

Molecular Reproduction
Michael Griswold SMB Interests: Role of Sertoli cells in mammalian spermatogenesis.	Pat Hunt SMB Interests: Mammalian germ cell development and meiotic cell cycle control.
Mary Hunzicker-Dunn SMB Interests: Signaling pathways leading to activation of target genes in ovarian granulosa cells directed by follicle-stimulating hormone or luteinizing hormone.	Kwan Hee Kim SMB Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.
John Nilson SMB Interests: Molecular mechanisms underlying temporal, spatial, and hormonal regulation of gene expression in pituitary gonadotropes. Developing mouse models that allow mechanistic interrogation of the hypothalamic-pituitary-gonadal (HGP) axis within a physiological setting.	Jon Oatley SMB Interests: Investigations are aimed at deciphering the molecular mechanisms that control fate decisions of germline stem cells and the determinants of the stem cell niche in mammalian testes.
James Pru Animal Sciences Interests: Maternal-embryonic interactions and endometrial regeneration.	Kenneth Roberts SMB Interests: Epididymal maturation and sperm function.
Thomas Spencer Animal Sciences Interests: Developmental Biology and function of the uterus and placenta.	Gary Thorgaard SBS Interests: Genetic analysis of complex traits in trout and salmon.

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