School of Molecular Biosciences

SMB Faculty Research Interests

Biochemistry & Structural Biology

Margaret Black
SMB
Interests: Nucleotide metabolism.
John Browse
IBC
Interests: Lipids in membrane function and cellular signaling.
Bill Davis
SMB
Interests: DNA oxidative damage and repair.
Lisa Gloss
SMB
Interests: Protein folding and macromolecular assembly: histones, the nucleosome and halophilic enzymes.
Joseph Harding
IPN 
Interests: Role of neuropeptides in brain-angiotensin system.
Chul Hee Kang
Chemistry
Interests: Calcium metabolism in cardiac myocyte and cardiac side effect of pharmaceutical compounds.
Mark Lange
IBC
Interests: Isoprenoid metabolism in plants.
Raymond Reeves
SMB
Interests: HMGA regulation of transcription.
Susan Wang
SMB
Interests: Radical mechanisms in enzyme catalysis.
Luying Xun
SMB
Interests: Microbial degradation of xenobiotics.
   

 

Cell Biology and Cellular Signaling

John Alderete
SMB
Interests: The study of parasite and host cell-tissue interactions focused on proteins that contribute to infection and disease pathogenesis.
John Browse
IBC
Interests: Lipids in membrane function and cellular signaling.
Cynthia Cooper
SMB
Interests: Zebrafish developmental mechanisms.
Joseph Harding
IPN 
Interests: Role of neuropeptides in brain-angiotensin system.
Chengtao Her
SMB
Interests: Mammalian DNA mismatch repair pathways.
Mary Hunzicker-Dunn
SMB
Interests: Signaling pathways leading to activation of target genes in ovarian granulosa cells directed by follicle-stimulating hormone or luteinizing hormone.
Jonathan Jones
SMB
Interest: Understanding how the behavior of epithelial cells is regulated by signaling initiated by ligand (extracellular matrix)-receptor interaction.
Kwan Hee Kim
SMB
Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.
Nancy Magnuson
SMB
Interests: Role of Pim-1 cellular proliferation and differentiation.
Eric Shelden
SMB
Interests: Shock proteins in zebrafish development, regeneration and aging.
Jennifer Watts
SMB
Interests: Genetics and genomics of lipid metabolism and fat storage in C. elegans.
 
   

Chromatin, DNA Repair and Cancer

Wenfeng An
SMB
Interests: Mechanisms of mammalian LINE-1 retrotransposition and applications in functional genomics.
Margaret Black
SMB
Interests: Suicide gene therapy of cancer.
Weihang Chai
SMB
Interests: Telomere structure, maintenance and function.
Bill Davis
SMB
Interests: DNA oxidative damage and repair.
Lisa Gloss
SMB
Interests: Protein folding and macromolecular assembly: histones, the nucleosome and halophilic enzymes.
Cynthia Haseltine
SMB
Interests: Mechanisms of homologous recombination and cellular responses to DNA damage in hyperthermophilic archaeal microbes.
Terry Hassold
SMB
Interests: Meitoic chromosome abnormalities.
Chengtao Her
SMB
Interests: Mammalian DNA mismatch repair pathways.
Chul Hee Kang
SMB
Interests: Calcium metabolism in cardiac myocyte and cardiac side effect of pharmaceutical compounds.
Nancy Magnuson
SMB
Interests: Role of Pim-1 cellular proliferation and differentiation.
Raymond Reeves
SMB
Interests: HMGA regulation of transcription.
Steven Roberts
SMB
Interests: Genome dynamics: mechanisms of mutation and chromosome alteration that contribute to human disease.  Mutagenesis of ssDNA in cancer.
Michael Smerdon
SMB
Interests: DNA excision repair in the context of chromatin structure.
Grant Trobridge
Pharmaceutical Sciences
Interests: Oncogene discovery using retroviruses.
John Wyrick
SMB
Interests: Histone modifications in global gene expression.
 
   

Microbial Genetics, Physiology and Infectious Disease

Hector Aguilar-Carreno
VMP
Interests: Entry mechanisms of highly pathogenic zoonotic viruses into mammalian cells.
John Alderete
SMB
Interests: The study of parasite and host cell-tissue interactions focused on proteins that contribute to infection and disease pathogenesis.
Kelly Brayton
Vet. Micro. Path.
Interests: Infectious diseases, microbial genomics, mechanisms of persistence.
Doug Call
VMP
Interests: Evolution and persistence of antibiotic resistance; molecular epidemiology; comparative genomics, transcriptomics, and proteomics of pathogens; detection pathogens in complex matrices; and aquaculture health.
Matthias Hess
SMB(TriCities)
Interests: Enhancing our understanding of microbial systems and how microbial communities and single microbes shape the world we live in.
Michael Kahn
SMB and IBC
Interests: Genetics, genomics and metabolism of plant-microbe interactions.
Leigh Knodler
Paul Allen School for Global Animal Health 
Interests: Microbial pathogenesis of enteric infections, Salmonella-intestinal epithelial cell interactions .
Michael Konkel
SMB
Interests: Campylobacter jejuni pathogenic determinants.
Audrey Lau
Vet. Micro Path.
Interests: Host-pathogen interactions in Apicomplexan parasites using microbial genomics and proteomic approaches. I am also interested in vaccine and drug discovery.
Anthony Nicola
VMP
Interests: Cell biology of virus-host interactions, herpesviruses, viral entry, membrane fusion, envelope glycoproteins, viral pathogenesis.
Linda Thomashow
USDA Research Geneticist
Interests: Pseudomonas genes involved in interactions with wheat.
Grant Trobridge
Pharmaceutical Sciences
Interests: Stem cell gene therapy for HIV infection.
Susan Wang
SMB
Interests: Radical mechanisms in enzyme catalysis.
Luying Xun
SMB
Interests: Microbial degradation of xenobiotics.

Molecular Genetics, Gene Regulation and Chromosome Biology

Wenfeng An
SMB
Interests: Mechanisms of mammalian LINE-1 retrotransposition and applications in functional genomics.
Weihang Chai
SMB
Interests: Telomere structure, maintenance and function.
Cynthia Cooper
SMB
Interests: Zebrafish developmental mechanisms.
Michael Griswold
SMB
Interests: Role of Sertoli cells in mammalian spermatogenesis.
Cynthia Haseltine
Assistant Professor, SMB
Interests: Mechanisms of homologous recombination and cellular responses to DNA damage in hyperthermophilic archaeal microbes.
Terry Hassold
SMB
Interests: Meitoic chromosome abnormalities.
Pat Hunt
SMB
Interests: Mammalian germ cell development and meiotic cell cycle control.
Kwan Hee Kim
SMB
Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.
Michael Konkel
SMB
Interests: Campylobacter jejuni pathogenic determinants.
John Nilson
SMB
Interests: Molecular mechanisms underlying temporal, spatial, and hormonal regulation of gene expression in pituitary gonadotropes. Developing mouse models that allow mechanistic interrogation of the hypothalamic-pituitary-gonadal (HGP) axis within a physiological setting.
Steven Roberts
SMB
Interests: Genome dynamics: mechanisms of mutation and chromosome alteration that contribute to human disease.  Mutagenesis of ssDNA in cancer.
B. Dan Rodgers
Animal Sciences
Interests: Molecular endocrinology and genomics of muscle development.
Eric Shelden
SMB
Interests: Heat shock proteins in drug resistance.
Michael Smerdon
SMB
Interests: DNA excision repair in the context of chromatin structure.
Gary Thorgaard
SBS
Interests: Genetic analysis of complex traits in trout and salmon.
Jennifer Watts
SMB
Interests: Genetics and genomics of lipid metabolism and fat storage in C. elegans.
 John Wyrick
SMB
Interests: Histone modifications in global gene expression.
 
   

Molecular Reproduction

Michael Griswold
SMB
Interests: Role of Sertoli cells in mammalian spermatogenesis.
Pat Hunt
SMB
Interests: Mammalian germ cell development and meiotic cell cycle control.
Mary Hunzicker-Dunn
SMB
Interests: Signaling pathways leading to activation of target genes in ovarian granulosa cells directed by follicle-stimulating hormone or luteinizing hormone.
Kwan Hee Kim
SMB
Interests: Vitamin A and retinoic acid receptors in spermatogenesis and testis development.
John Nilson
SMB
Interests: Molecular mechanisms underlying temporal, spatial, and hormonal regulation of gene expression in pituitary gonadotropes. Developing mouse models that allow mechanistic interrogation of the hypothalamic-pituitary-gonadal (HGP) axis within a physiological setting.
Jon Oatley
SMB
Interests: Investigations are aimed at deciphering the molecular mechanisms that control fate decisions of germline stem cells and the determinants of the stem cell niche in mammalian testes.
James Pru
Animal Sciences
Interests: Maternal-embryonic interactions and endometrial regeneration.
Kenneth Roberts
SMB
Interests: Epididymal maturation and sperm function.
Thomas Spencer
Animal Sciences
Interests: Developmental Biology and function of the uterus and placenta.
Gary Thorgaard
SBS
Interests: Genetic analysis of complex traits in trout and salmon.

School of Molecular Biosciences, SMB, PO Box 647520, Life Sciences Building 202, Pullman, WA 99164-7520 phone: 509-335-8751, fax: 509-335-4159
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